Repair of acne scars with Dermicol-P35
Acne vulgaris is a prevalent skin condition that can cause disfiguring residual scarring. While the complete removal of acne scars is unlikely, several treatments exist that can improve the appearance of acne scars.
Dermal fillers offer a simple, nonsurgical corrective procedure that can provide improved skin texture. Dermicol-P35 (Evolence [Ortho Dermatologics, Skillman, NJ]) is a new, highly purified, ribose cross-linked, porcine collagen-based dermal filler that has demonstrated low immunogenicity and results that persist for at least 12 months.
This article presents the aesthetic results of a male patient treated with Dermicol-P35 for severe facial acne scars.
Repair of acne scars with Dermicol-P35.
Aesthet Surg J. 2009 May-Jun; 29(3 Suppl): S16-8Smith KC (Hubmed)
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Acne Scar Medications | Adult Acne Medications | Sulfur Acne Medications | Oral Acne Medications
Minocycline-induced skin pigmentation
Minocycline is a commonly used antibiotic for long-term treatment of acne vulgaris. A well-documented and cosmetically displeasing side effect is skin pigmentation.
Three distinct types occur: Type I, blue-black/grey pigment on the face in areas of scarring or inflammation associated with acne; type II, blue-grey pigment on normal skin on the shins and forearms; type III, diffuse muddy-brown discoloration in areas of sun exposure.
Types I and II stain for iron and melanin extracellularly and within macrophages in the dermis. Type III shows nonspecific increased melanin in basal keratinocytes and dermal melanophages staining for melanin only.
The etiology of this pigmentation is unknown, but may be related to polymerized reactive metabolites, insoluble chelation products, and lengthy treatment durations of minocycline compared to other tetracyclines.
Types I and II tend to resolve slowly over time, whereas type III persists indefinitely. Treatment involves early recognition, discontinuation of the drug, sun protection, and laser for persistent pigmentation.
Minocycline-induced skin pigmentation
Acta Dermatovenerol Croat. 2009; 17(2): 123-6Geria AN, Tajirian AL, Kihiczak G, Schwartz RA(Hubmed)
