Dehydroepiandrosterone supplementation in assisted reproduction
To present the possible positive effect of dehydroepiandrosterone administration in assisted reproduction and especially in poor responders, women with diminished ovarian reserve, premature ovarian failure and premature ovarian aging in the course of ovarian stimulation protocols followed either by intrauterine insemination or IVF.
RECENT FINDINGS:
Overall, 50-75 mg of dehydroepiandrosterone supplementation for at least 4 months may either result in natural conception or considerably improves intrauterine insemination and IVF outcome and pregnancy rates to women with confirmed diminished ovarian reserve, premature ovarian failure or premature ovarian aging. Positive effect has been reported to oocyte and embryo quality, even to women aged 40-47 years. The number of euploid embryos is increased, and miscarriage rate is decreased.
SUMMARY:
Although more data on the dehydroepiandrosterone effect on assisted reproduction are needed, results obtained over the last few years confirm the improvement of oocyte production and pregnancy rates. No significant side effects are reported, and those include mainly hirstusism and acne.
Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results.
Curr Opin Obstet Gynecol. 2009 Aug; 21(4): 306-8Mamas L, Mamas E
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RECENT FINDINGS:
Overall, 50-75 mg of dehydroepiandrosterone supplementation for at least 4 months may either result in natural conception or considerably improves intrauterine insemination and IVF outcome and pregnancy rates to women with confirmed diminished ovarian reserve, premature ovarian failure or premature ovarian aging. Positive effect has been reported to oocyte and embryo quality, even to women aged 40-47 years. The number of euploid embryos is increased, and miscarriage rate is decreased.
SUMMARY:
Although more data on the dehydroepiandrosterone effect on assisted reproduction are needed, results obtained over the last few years confirm the improvement of oocyte production and pregnancy rates. No significant side effects are reported, and those include mainly hirstusism and acne.
Dehydroepiandrosterone supplementation in assisted reproduction: rationale and results.
Curr Opin Obstet Gynecol. 2009 Aug; 21(4): 306-8Mamas L, Mamas E
Highlight:
Advancement in benzoyl peroxide-based acne treatment
Pathogenesis of acne vulgaris: recent advances
Comparative efficacy and safety results of two topical combination
Quality of medical care of patients with acne vulgaris in Germany
Sulfur Acne Medications for Severe Acne
Related:
Temporary aid for needy families controls women's reproduction
Denial of reproductive freedom: controlling women's reproduction
Women's reproduction
Women as reproduction machines and pleasure objects?
Vaginal Plastic Surgery - Women Reproduction Health
